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AKA The clinic stack · Growth hormone pulse for sleep and body composition

GH pulse stack

CJC-1295 (no-DAC) plus Ipamorelin for sleep and body composition.

Last reviewed April 27, 2026 by Editorial team · 2 compounds

Information on this page is sourced from community use patterns and published research on each component. Educational only — not medical advice.

TL;DR

  • What it is: The classic growth hormone secretagogue stack.
  • Best for: Growth hormone pulse for sleep and body composition
  • Evidence level:limitedEach compound has small clinical PK studies but no large RCTs in healthy adults for body composition or sleep. The combination has not been studied as a fixed protocol in humans.

CYCLE

8-12 weeks on, 4 weeks off

CompoundRoleDoseScheduleRoute
CJC-1295

No-DAC variant, pre-bed only.

GHRH analog100 mcg no-DAC (pre-bed, stacked with ipamorelin 200-300 mcg)Once daily (no-DAC) or weekly (DAC)Subcutaneous
Ipamorelin

Pre-bed, in the same syringe as CJC-1295.

GHS-R1a agonist200-300 mcg1-3x dailySubcutaneous

Why it works

CJC-1295 stimulates GH release via the GHRH receptor, Ipamorelin stimulates it via the ghrelin receptor. The two pathways are complementary, which is why the combination is more potent than either alone. The pulse occurs naturally during deep sleep, pre-bed dosing aligns with that pulse.

Cautions

GH stimulation is contraindicated for anyone with active or suspected cancer, severe diabetes, or pituitary disorders. Eat at least 90 minutes before dosing -- a meal blunts the GH pulse. Cycle off to avoid receptor desensitization.

Compounds in this stack

Sources

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